Therapeutic Expertise
Image Core Lab is your trusted imaging partner for global clinical trials and radiology AI development. Our board-certified radiologists deliver protocol-driven reads guided by validated scoring systems across all major therapeutic areas.
Oncology Imaging
Oncology trials account for a majority of our clinical imaging work, making it the cornerstone of Image Core Lab’s therapeutic expertise. We deliver high-quality imaging reads that meet regulatory standards globally.
Key Focus Areas
- Solid Tumors: Breast, Colorectal, Ovarian, Prostate, Pancreatic, Lung, Bladder, Kidney, Stomach, Skin, Brain
- Hematologic Cancers: Lymphomas, Myeloma, Leukemia
Our radiologists are extensively trained in the criteria to maintain scoring consistency in blinded, multicenter environments.
We objectively measure changes and treatment responses adding a layer of precision beyond conventional size-based criteria. These quantitative endpoints enhance confidence in assessing disease progression and therapeutic effects.
| Focus Area | RECIST 1.1 | iRECIST | irRC | LUGANO | IMWG | RANO | iwCLL |
|---|---|---|---|---|---|---|---|
| Bladder | – | – | – | – | |||
| Breast | – | – | – | – | |||
| Colorectal | – | – | – | – | |||
| Glioma | – | – | – | – | – | – | |
| Kidney | – | – | – | – | |||
| Leukemia | – | – | – | – | – | – | |
| Lung | – | – | – | – | |||
| Lymphomas | – | – | – | – | – | – | |
| Melanoma | – | – | – | – | |||
| Myeloma | – | – | – | – | – | – | |
| Ovarian | – | – | – | – | |||
| Pancreatic | – | – | – | – | |||
| Prostate | – | – | – | – | |||
| Stomach | – | – | – | – |
Musculoskeletal Imaging
Our expertise combines subspecialty radiology with standardized scoring systems such as RAMRIS and Kellgren-Lawrence to deliver precise reads critical for MSK therapeutic development and device validation.
Key Focus Areas
- Rheumatoid Arthritis
- Osteoporosis
- Osteoarthritis
- Degenerative Disc Disease
While clinical trials remain at the core, our MSK expertise extends to orthopedic device validation and radiology AI development.
| Focus Area | vdH-mTSS | RAMRIS | Fracture Healing Metrics | Kellgren-Lawrence Score |
|---|---|---|---|---|
| Degenerative Disc Disease | – | – | – | |
| Osteoarthritis | – | – | – | |
| Osteoporosis | – | – | – | |
| Rheumatoid Arthritis | – | – |
Gastrointestinal (GI) Imaging
Key Focus Areas
- Inflammatory Bowel Disease (IBD)
- Crohn’s Disease
- Ulcerative Colitis
These chronic and often debilitating conditions demand precise imaging endpoints. We provide expert, protocol-driven reads across GI indications by applying scoring systems.
With experience in ulcerative colitis studies, we provide clinical-grade interpretations aligned with regulatory endpoints.
| Focus Area | Mayo Endoscopic Score | Endoscopic Indexes |
|---|---|---|
| Crohn’s Disease | – | |
| Inflammatory Bowel Disease | ||
| Ulcerative Colitis |
Cardiovascular Imaging
At Image Core Lab, we support trials across a spectrum of cardiovascular conditions delivering precise, reproducible measurements essential for endpoint validation and regulatory submission.
Key Focus Areas
- Cardiomyopathies
- Congenital Heart Defects
- Coronary Artery Disease
- Heart Failure
- Valvular Heart Disease
Our subspecialist radiologists support the various imaging modalities and implement standardized imaging criteria.
Each read is aligned with trial-specific protocols and regulatory expectations, with centralized interpretation minimizing inter-reader variability across global multicenter studies.
| Focus Area | LVEF | Calcium Scoring | SYNTAX Score | Gensini Score | Duke CAD Index | CAD-RADS 2.0 | MRI Stress Perfusion |
|---|---|---|---|---|---|---|---|
| Cardiomyo-pathies | – | – | – | – | – | ||
| Congenital Heart Defects | – | – | – | – | – | ||
| Coronary Artery Disease (CAD) | |||||||
| Heart Failure | – | – | – | – | |||
| Valvular Heart Disease | – | – | – | – |
Neuroimaging
Key Focus Areas
- Stroke
- Alzheimer’s Disease
- Parkinson’s Disease
- Epilepsy
- Brain Injury
- Multiple Sclerosis
Our board-certified neuroradiologists specialize in interpreting scans for a wide spectrum of central nervous system conditions.
We support the development and validation of neuro-focused radiology AI solutions.
| Focus Area | McDonald Criteria | Volumetric Assessment |
|---|---|---|
| Alzheimer’s Disease | – | |
| Stroke | – | |
| Parkinson’s Disease | – | |
| Epilepsy | – | |
| Brain Injury (TBI) | – | |
| Multiple Sclerosis |
Get in touch with us
Feel free to contact any time by filling the form given below. Our customer support team or sales team will get in touch with you at the earliest
Frequently Asked Questions
What is therapeutic imaging in clinical trials?
Therapeutic imaging involves using medical imaging to evaluate disease progression, treatment response, and clinical endpoints within a specific therapeutic area such as oncology, MSK, or CNS.